Host: The Japanese Pharmacological Society
Name : The 97th Annual Meeting of the Japanese Pharmacological Society
Number : 97
Location : [in Japanese]
Date : December 14, 2023 - December 16, 2023
A fundamental question in understanding tissue development is how resident stem cells or multipotent progenitors give rise to the various cell types in appropriate numbers and at the right locations to achieve tissue organization. Neural stem/progenitor cells (NPCs) in the mammalian neocortex initially divide symmetrically to increase their pool size (expansion phase). They then start to divide asymmetrically and give rise to neuronal and glial cell types in a region- and developmental stage–dependent manner. In this talk, I will present data regarding the mechanisms underlying the transition from the expansion phase to the neurogenic phase and discuss their potential role in psychiatric diseases such as autism spectrum disorder.
I would also like to present our results regarding signaling pathways involved in innate immunity that regulate cell fate after viral infection.
