2000 年 60 巻 1 号 p. 62-70
We have developed a deglutition aid jelly that will allow almost all solid preparations to be barrier-free dosage form preparations. During development, an evaluation test for application was performed in a healthy care facility for the elderly, and a survey on properties, color, taste and container, which are required for the jelly, was conducted. Based on results of the survey, a jelly like wafer was obtained under the following conditions. An agar was chosen as a main ingredient. Six percent of erythritol and sorbitol was employed for a good filling performance and to retain 10-30 g/cm2 of jelly intension and about 5% of the loss of water content. Other gelatinizers and flavors are also combined, each at a lower additional level. Since this product has no interaction with medicines, no bafflement for disintegration or dissolubility of the existing tablets, facility of taking it even for children and people with difficulty in swallowing, no risk of taking it by mistake, and securement for safety, this product therefore could contribute to the improvement of QOL for people who feel burdened by taking medicines.