Waveform Analysis of the Brachial-ankle Pulse Wave Velocity in Hemiplegic Stroke Patients and Healthy Volunteers: A Pilot Study

Abstract

[Purpose] Brachial-ankle pulse wave velocity (BaPWV), which has been reported as an index of arterial stiffness, is very closely related to cardiovascular risk factors. A high BaPWV indicates high cardiovascular risk. However, BaPWV and pressure waveforms after stroke are not fully understood. [Methods] BaPWV was measured in thirty-two subjects (twenty-two healthy volunteers and ten stroke patients) while they were in the supine position. It was measured in their bilateral upper and lower extremities. [Results] BaPWV was significantly increased in the stroke group compared with the healthy volunteers. It was also significantly increased on both the affected and non-affected sides of stroke patients in the stroke group. Furthermore, analysis of the pressure waveforms showed that the peak pressure was significantly increased in the stroke group compared with the control group. The peak pressure on both the affected and non-affected sides was also significantly greater than in the control group. However, the rise and decay times were significantly decreased in the stroke group compared with the control group. The rise and decay time on both the affected and non-affected sides were also significantly more decreased than in the control group. [Conclusion] The results demonstrated that increased BaPWV and changed pulse waves are closely associated with the pathologic states of hemiplegic stroke patients.