Effects of short-term immobilization of the upper limb on the somatosensory pathway: a study of short-latency somatosensory evoked potentials

Abstract

[Purpose] Previous studies have reported that the nervous system is influenced during short-term cast immobilization. However, the effects of short-term inactivity on somatosensory information processing systems are not well understood. This study investigated the effect of 10 h of upper limb immobilization on the somatosensory pathway using short-latency somatosensory evoked potentials. [Participants and Methods] Twenty right-handed healthy participants (mean age 21.7 years) were enrolled in this study. The participants’ left hands and forearms were wrapped in a soft bandage at a 90° elbow flexed position. The participants were instructed not to move their left hand for 10 h. To obtain short-latency somatosensory evoked potentials, we used a multimodal evoked potential system. The left median nerve was electrically stimulated at a rate of 5 Hz for a duration of 0.2 ms. The intensity of the stimulus was adjusted to induce mild twitches of the thumb. The amplitudes and latencies of the short-latency somatosensory evoked potential components (N9, N13, and N20) were measured before and after immobilization. [Results] The amplitude of the N9 component significantly increased after immobilization. [Conclusion] Our results indicated that the changes in the excitability of the peripheral somatosensory nerve were due to 10 h of inactivity.