下垂体別出幼若雌鼠におけるSheep ICSH投与成績
1960 年 5 巻 4 号 p. 139-141
詳細
1960 年 5 巻 4 号 p. 139-141
This is a result of experiments which confirmed the biological activities of a preparation of sheep ICSH (LH) used in the course of studies on the actions of gonadotrophins.
The effects of relatively large doses of the preparation of ICSH on the reproductive system of hypophysectomized immature female rats were studied.
The significant increase of ovarian weight and the follicular development was not observed in all dosage levels. The interstitial cells were, already, repaired at a dose of 50γ which was the minimal dose adopted in this experiment. No corpus luteum was formed even at a large dose of ICSH (1000 γ). The uterine weight increased, slightly, at doses more than 200 γ.
These results were almost the same as those given by the previous workers who used the pure sheep or porcine ICSH.
