Journal of Reproduction and Development
収録数 4,171本
(更新日 2025/04/02)
Online ISSN : 1348-4400
Print ISSN : 0916-8818
ISSN-L : 0916-8818
ジャーナル 査読 オープンアクセス 早期公開
DOAJ Scopus Pubmed
おすすめ記事
71 巻 (2025) 1 号 p. 10-16
Can Humanity Thrive Beyond the Galaxy? もっと読む
編集者のコメント

Cover Story:
The expansion of humanity into space is inevitable. However, human reproduction within space habitats or on extraterrestrial planets poses profound challenges including harmful mutations caused by cosmic radiation and abnormal development of embryos and fetuses in non-terrestrial gravitational environments. Moreover, colonizing other star systems necessitates the transportation of thousands of individuals from each animal species to the target planet to prevent inbreeding-related degeneration. Looking further ahead, as humans disperse throughout the galaxy, the imperative to preserve all genetic resources from Earth permanently and securely becomes paramount. This review examines the issues that must be addressed to ensure human prosperity in space, as well as the challenges that need to be resolved for the transport and long-term preservation of vast genetic resources (Wakayama S. and Wakayama T. Can Humanity Thrive Beyond the Galaxy? pp. 10-16).

70 巻 (2024) 6 号 p. 411-417
Addition of granulocyte macrophage colony stimulating factor (GM-CSF) during in vitro oocyte maturation improves embryo development in a mouse model of advanced maternal age もっと読む
編集者のコメント

Cover Story:
Study by Saini et al. investigated the effects of adding Granulocyte-macrophage colony-stimulating factor (GM-CSF) during in vitro maturation (IVM) on oocyte quality in a mouse model of advanced maternal age (Saini et al.: Addition of granulocyte macrophage colony stimulating factor (GM-CSF) during in vitro oocyte maturation improves embryo development in a mouse model of advanced maternal age. pp. 411–417). Oocytes from older female mice were treated with GM-CSF, and several developmental competence measures were assessed. The treatment tended to increase fertilisation rates (76.19 vs. 82.03; P = 0.07) while increasing blastocyst rates 51.10 vs. 61.52; P < 0.01), and the number of good quality of blastocysts (33.31 vs. 44.13; P < 0.05), along with increased inner cell mass and total cell number. GM-CSF also increased mitochondrial membrane potential. However, it did not affect spindle formation or chromosome alignment. These findings indicate that GM-CSF could improve oocyte quality in women of advanced maternal age by improving embryo development and mitochondrial function.

70 巻 (2024) 5 号 p. 286-295
Autophagy in the corpus luteum correlates with tissue growth in pregnant rats もっと読む
編集者のコメント

Cover Story:
The temporally regulated function and structure of the corpus luteum (CL) are critical for the establishment, maintenance, and termination of pregnancy across various animal species. Oishi et al. found that autophagic activity in the rat CL fluctuates in correlation with tissue weight rather than progesterone (P4) production (Oishi et al., Autophagy in the corpus luteum correlates with tissue growth in pregnant rats. pp. 286–295). Their perturbation experiment using a chemical inhibitor suggests that autophagy contributes to increasing the size of luteal steroidogenic cells and precisely modulates their P4 secretion. The dual nature of autophagy, which controls cellular survival or death, may be implicated in the reciprocal regulation of luteal P4 secretion to determine the appropriate gestational length in species whose P4 production depends solely on CL.

すべてのおすすめ記事を見る
月間アクセス数ランキング (2025年03月)
このページを共有する
過去の巻号を選ぶ
feedback
Top