抄録
Cysteamine afforded marked protection against the effects of X-irradiation on both dose-dependent accumulation of fructose-1, 6-diphosphate and ATP depletion to an approximately equivalent extent, giving the dose-reduction factor of about 2. This was considered as support for the view that both phenomena are closely related and arose from a common event. Little protection was afforded under the same conditions against irradiation-induced accumulation of pyruvate and lactate in the lower dose range. Possible mechanisms underlying these phenomena are discussed.