抄録
Cultured Human Normal Cells, GM 05389, were irradiated with heavy-ion beams and the chromosomal aberrations and its repairing kinetics were analysed by prematurely chromosome condencation method (PCC method) using calyculin A. The cells were irradiated with 290 MeV C, 490 MeV Si, 500 MeV Ar and 500 MeV Fe ions at HIMAC facility of the National Institute of Radiobiological Sciences in Chiba. Various LET values were selected at the irradiations of these ions. These were 13, 120, 136, 370 and 440 keV/mm. Chromatid-type breaks, isochromatid breaks and exchanges were scored for the samples from the cells keeping with various incubation time after irradiation. Some specific characteristics of repairing kinetecs were clarified for chormosomal aberrations induced by heavy-ion beams. [J Radiat Res 44:400-401 (2003)]
