The System of Parallel Cell Manipulation by using Integrated Gel Actuator

Abstract

On-chip actuator is an essential component to realize single cell analysis in microfluidic device. Previously, we proposed a light-driven gel actuator for single cell manipulations. The advantage of this drive method is it enables local heating for integration of large number of actuators on a microfluidic chip. In this study, we present multiple cell manipulations system by using integrated light-driven gel actuators. We construct the microscope to irradiate patterned light by using digital mirror device. Therefore, we can drive multiple gel actuators selectively. Finally, we demonstrate an example of cell manipulations by using integrated gel actuators and the constructed system.