大気圧低温プラズマ及び臍帯血による低酸素脳症治療を目的とした血液に対するプラズマ照射条件の検討

抄録

　In recent years, atmospheric-pressure plasmas are applied in the medical applications. Although the mechanism of action remains unclear, new biomedical applications of plasma have been found. Experiments using atmospheric pressure plasmas confirmed several effects such as burn healing with angiogenesis. In addition, umbilical cord blood is expected to be applied to the field of regenerative medicine due to the presence of mesenchymal stem cells. We have been focusing treatment of Hypoxic Ischemic Encephalopathy (HIE). HIE caused by the discontinuation of blood supplied means that a part of the brain is necrotized and a brain function is impaired. There is no fundamental therapy for HIE except for symptomatic therapy as of now. Because of preservation and recovery of brain functions can be expected, as a study on HIE treatment, we consider and report on a method of administrating atmospheric-pressure plasma and umbilical cord blood to HIE model rat.