Recently, biomedical terminologies and ontologies have been publishing a wide variety of data. For the integration of them, it is important to overcome the conceptual discrepancy. In this article, we discuss ontological issues of integrating knowledge of abnormal states in existing biomedical resources. Next, we show an approach for the solution with our ontology of abnormal states. Then, by applying Linked Data technique, we develop a prototype system for linking our ontology as a hub of existing resources. Our approach will bring benefits for promoting interoperability across heterogeneous data according to the meaning of concepts and contribute to developing knowledge integration infrastructure for disease.
