人工臓器
Online ISSN : 1883-6097
Print ISSN : 0300-0818
ISSN-L : 0300-0818
高分子材料の結晶性と抗血栓性
由井 伸彦高橋 洋一讃井 浩平緒方 直哉片岡 一則岡野 光夫桜井 靖久
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1981 年 10 巻 6 号 p. 1070-1073

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Effect of crystallinity of polyamides on blood coagulation were investigated in terms of adhesion behavior of blood platelets. Polyamides having various crystallinity were synthesized and were annealed after coating on the glass beads. Then, platelets adhesion on these polyamides was evaluated by Microsphere column method. It was found that there was a correlation between adhesivity of platelets and crystallinity of polyamide. Transmission electron microscopic observation revealed that these polyamide surfaces formed microdomain structure composed of crystalline domains and amorphous domains. From these results, it was concluded that the distribution of microdomains (crystalline-amorphous) played an important role in platelets adhesion.

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