Hemopurification therapy is operated at present based upon each doctor's judgement. The purpose of this research is to establish the automatic control of dialysis therapy using desk-top computer.
At first, removal dynamics of uremic toxin in a body and in a module was analysed both with pool model and mass transfer model. Applying these techniques, CL, DB and CB(0) can be obtained from dialysate concentration alone. The change of blood concentration with time can be also estimated only from the analysis of dialysate concentration. The calculated values of the blood concentration were found to agree well with the experimental values.
Next, an optimum schedule of the dialysis therapy was derived from the concept of maximum solute concentration in stable periods. The condition of the therapy would be chosen to fit this schedule.
