抄録
A newly developed plasma separator “PLASMAX”, made of PMMA (polymethylmethacrylate) hollow fiber, was evaluated, for its efficiency to filtrate plasma and its blood compatibility in 20 dog experiments.
The results are summarized below; 1. The optimal transmembrane pressure was under 30mmHg.
2. Plasma flux was mainly dependent on blood flow rate (QB) and was nearly proportional to QB. It was about 2L/hour at QB=6L/hour.
3. Sieving coefficients for various proteins were almost unity and remained so throughout the experiment which extended for up to 3 hours.
4. WBC platelets, fibrinogen and coagulation factors decreased during the early stage of plasma separation but seemed to be within acceptable ranges.
