Artificial bone of alumina ceramics---Biological response in the costal cartilage

Abstract

Polycrystalline ceramics was found to be an excellent biomaterial in its biological affinity to the cartilage tissue as well as to the bone. Namely, cartilage healed rapidly and correctly without inflammation and foreign-body reaction in 8 weeks, and matured well with acidmucopolysaccharide-rich tissue. It adhered to the ceramics four or eight times as strongly as to the steel. Scanning electron microscope showed cartilage tissue remained to adhere onto the surface of ceramics, which was pulled out, but not onto the steel.