Abstract
In Japan, hepatitis B infection occurs in 7% of patients undergoing blood or plasma transfusion. Now, we have been developing the immunoadsorbent filter for removing hepatitis B virus, by means of immobilized HBs antibody. This report represented the study on carrier which is capable to link a lot of HBs antibody and to adsorb a lot of HBs antigen. The results were as follours: 1. The most effective carrier was anti-HBs treated cross-linked Gantrez, in addition to anti-HBs treated Sepharose. 2. When 1.0ml of HBs antigen positive plasma was filtrated through 0.2g of anti-HBs treated cross linked Gantrez, HBs antigen titer of plasma fell sharply from 210 to 23-24. It is supposed that the next subject of this experiment is the study on manufacture of cross-linked Gantrez.
