Abstract
Prosthetic grafts were modified by depositing on their surfaces with collagen or collagen-chondroitin sulfate complex by using glow discharge techniques and the veins of dogs were replaced with them. Biocompatibility and antithromobogenecity of the grafts were found to be enhanced by this treatment, especially with collagen-chondroitin sulfate complex. Fibrin formation and platelet adhesion on the grafts were inhibited and the patency extended for eleven months after replacement.