Abstract
We tried plasmapheresis on different cases of SLE. Case 1 was a CIC positive case with an acute lupus nephritis. Plasmapheresis combined with hemodialysis caused the urinary output to increase again and the serum creatinine coefficient to drop. And attempt was made to drop hemodialysis. Case 2 had an acute case of renal failure. But it was CIC negative. No improvement was observed with regard to urinary output and serum creatinine coefficient. Case 3 showed Raynaud's phenomenon and marked skin abnormalities. This case was CIC positive. With plasmapheresis, CIC turned negative and skin abnormalities disappeared. These results indicated that, as reported in a number of studies, plasmapheresis is effective for CIC positive cases in SLE. And the combination therapy with steroid is necessary.
