Abstract
The plasmapheresis with plasma exchange was performed for 71 times upon 24 patients using Haemonetics model 30. Thirteen of them suffered from postoperative hyperbilirubinemia and were included in the study. The plasmapheresis was applied upon these hyperbilirubinemic patients in order to reduce serum bilirubin level. The plasmapheresis seemed to be effective for hyperbilirubinemia following hepatectomy but not to be effective for hyperbilirubinemia among multiple organ failure patients. Therefore the indication of the plasmapheresis should be considered cautiously since it needs huge amounts of fresh frozen plasma.