Abstract
It is now gradually accepted that the sera of cancer patients contain the immune inhibitory factors which suppress a number of lymphocyte functions in vitro, increasing with the progress of the disease, Plasma exchange seems to be useful and adequate procedures to dilute or eliminate these inhibitory factors. In this paper, plasma exchange was combined with immunochemotherapy of the patients with advanced cancer and its effect was discussed. Nine patients underwent plasma excharge. Five of them had an partial response documented one or two weeks after the first plasma exchange, and various immunological parameters were remarkably improved. Combined treatment of plasma exchange and immunechemotherapy might be beneficial on cancer patients.
