Abstract
A program control system of circulating blood volume during hemofiltration has been developed, which is constructed from a continuous circulating blood volume measuring system, a micro-computer, and a substitution fluid infuser. In this system, hematocrit is calculated from the formulae as a function of electrical resistivities of blood and filtrate, which was given by Geddes and Gram. Then the circulating blood volume change, ΔBV, is calculated and the flow rate of the infuser is adjusted by the micro-computer. This system was applied to 8 patient in a total of 30 times and was found to keep the difference between actual and desired blood volume values within ±3%.