Abstract
Antithrombogenic catheter coated with heparinized hydrophilic polymerer (H-RSD) has been developed. During 82' to 83' this catheter has been used in 45 patients as the indwelling catheter in the central vein, and the antithrombogenicity of the catheter has been evaluated. The catheter was placed in the central vein for the period from 4 days to 105 days (mean 35 days). Thrombus formation due to the catheter was examined by clinical observation, and by scanning electromicroscopy of the surface of these catheter after removal from the patients. Thrombus formation on the surface of the H-RSD catheters was compared with that of the polyvinyl carolide catheters. Marked thrombus formation was observed on the inner surface of polyvinyl chrolide catheter, however the thrombus formation was minimum in case of H-BPS catheters. The blood compatibi lily of the H-RSD catheter is excellent. The H-RSD catheter is suitable for use as the indwelling catheters where long-standing antithrombogenicity is mandatory.
