-
[in Japanese]
1984 Volume 13 Issue 3 Pages
1037
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
-
[in Japanese]
1984 Volume 13 Issue 3 Pages
1039-1043
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
-
[in Japanese]
1984 Volume 13 Issue 3 Pages
1044-1045
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
-
[in Japanese]
1984 Volume 13 Issue 3 Pages
1046-1050
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
-
[in Japanese]
1984 Volume 13 Issue 3 Pages
1051-1053
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
-
[in Japanese]
1984 Volume 13 Issue 3 Pages
1054-1057
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
-
[in Japanese]
1984 Volume 13 Issue 3 Pages
1058-1062
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
-
[in Japanese]
1984 Volume 13 Issue 3 Pages
1063-1065
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
-
[in Japanese]
1984 Volume 13 Issue 3 Pages
1066-1071
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
-
[in Japanese]
1984 Volume 13 Issue 3 Pages
1072-1073
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
-
[in Japanese], [in Japanese], [in Japanese], [in Japanese]
1984 Volume 13 Issue 3 Pages
1074-1079
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
-
H. KUROSAWA, K. ONCHI, P.S. WALKER
1984 Volume 13 Issue 3 Pages
1080-1082
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
Basic researches, in addition to experience of clinical trials, of total knee prosthesis is very important. We performed motion analysis of the knee joint in 14 fresh cadaveric knees. The femoral condyles rotated on the tibia externally by average 20° in 0° to 120° of flexion. Forces at the interface between tibial component and bone were analysed in 10 fresh cadaveric knees. Normal and shear force and moment at the interface markedly increased after incision of the posterior cruciate ligament. Importance of the retention of the posterior cruciate ligament was confirmed from the results.
View full abstract
-
S. YAMAMOTO, M. HACHINOTA, S. NAKATA, S. UEDA, S. YOKOTA, Y. KONDOH
1984 Volume 13 Issue 3 Pages
1083-1086
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
In 1970, the first case of total knee replacement using the Kodama-Yamamoto knee prosthesis was done. After about fourty_cases of surgery and researches on biomaterials of the prosthesis and biomechanics of the knee, it was developed into the Mark II. In order to get good results of total knee replacement, design of the prosthesis, surgical technique and selection of patients are very important.
View full abstract
-
T. SASAKI, S. MATSUNO, T. YAGI, J. MONJI, K. YASUDA, [in Japanese], K. ...
1984 Volume 13 Issue 3 Pages
1087-1090
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
This paper reviews our experience of 218 total knee replacements for deteriorated knees. A score of 85 to 100 points represents an excellent results; 70-84, a good result; 60 to 69, fair; and less than 60, poor. Overall, 78% were excellent or good for nonhinge group compared to 36% for hinge group, and also 78% were excellent or good for OA group compared to 64% for RA group. The higher complication rate has been detected in hinge group or RA group. The rate of revision was 7.3% in this series.
View full abstract
-
N. AKAMATSU, Y. BAMADA, H. FUKUSHIMA, I. NAKAJIMA, H. SATO, T. YAMAGUC ...
1984 Volume 13 Issue 3 Pages
1091-1093
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
knee prosthesis with hinge type is indicated for the cases of proximal end of tibia or distal end of femur occupied by large bone tumors, especially giant cell tumor of bone, in order to expect good function. We have developed total hinged knee prosthesis with low friction device since eight years before as acrylic and metallic ones were failed at breakage and material with much debris. In the follow-up study of cases treated with the latest total hinged knee prosthesis with low friction device, extension lag, infection, and poor range of motion are seen in many cases of proximal end of tibia in comparison with distal end of femur. The reason why such a different result between them takes place is that more frequent infection caused in trauma in the proximal end of tibia, becuase of less quantity of soft tissue, less resection of joint surface in the case of tumor in the distal end of femur, problem concerning reattachment of patellar ligament and so on. We have to noticefy that there are many problems on the case treated with hinged total knee prosthesis for bone tumor in the proximal end of tibia.
View full abstract
-
H. OONISHI, A. MAEDA, T. HAMAGUCHI, N. OKABE, T. NABESHIMA, T. KOIKE, ...
1984 Volume 13 Issue 3 Pages
1094-1098
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
We have succeeded in developing a cementless total knee prosthesis, in which alumina ceramics is employed for the part coming in contact with the bone and the combination of HDP with alumina ceramics for the sliding part. These components are suported especially on the cortical bone and subchondral bone of femur and tibia. We have performed by means of finite element method in determining the adequacy of the implant design and position and in understanding the contact behaviour of the implant-bone and the mechanical behavior of fixation of the implants.
View full abstract
-
T. MITSUI, S. NIWA, S. IWASAKI, K. KAITO, H. HASEGAWA, R. FURUKAWA, N. ...
1984 Volume 13 Issue 3 Pages
1099-1103
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
Gait analysis was carried out on 8 non-constrained total knee replacement patients with osteo arthrosis and an age-matched group of normals using the electro-goniometer, foot switch, force plate, foot print, cybex III. The group of patients with bilateral T. K. R. (group C) had a slightly shorter than normal step length. The groups of both side affected patients with unilaleral T. K. R. (group B) had a slightly prolonged support time of the gait cycle. On fllor reaction pattern, the each groups of patients had a decreasing peak 1 and flattening of double peak on the vertical component and the max. restraint A and the max. propulsion F on sagittal ccnnponent were decreased. The value of peak torque of knee extensor muscles was markedly reduced after total knee replacement even asymptomatic patients with excellent clinical results. The range of knee motion during level walking was quite similar to normals.
View full abstract
-
[in Japanese]
1984 Volume 13 Issue 3 Pages
1104
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
-
E. UDAGAWA
1984 Volume 13 Issue 3 Pages
1105-1108
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
On the basis of author's experience of total hip joint replacement for 626 joints, indications of the operation, especially for young patient, for highly dislocated hip, for case with both sides and for hip disturbance in ankylosing spondilytis, were discussed.
View full abstract
-
T. MASUDA, T. AZUMA, M. TTAKAHASHI, I. HASEGAWA, T. MATSUNO, K. HOSHII ...
1984 Volume 13 Issue 3 Pages
1109-1112
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
1. 68 cases or cemented total hip prostheses which had been operated on more than 5 years ago were studied with regards to “loosening”. Radiographic evidence of loosening of the acetabular and/or femoral components was shown in 27 hips, 40% of total cases. We should pay much attention to not only the choice of adequate prestheses but also cementing techniques.
2. Histological studies of the tissue at the interface of bone-cement interface in loosened prostheses revealed that there was a synovium-like membrane, and deep to the membrane foam cells and foreign body giant cells predominated. High levels PGE were detected in cases which showed massive bone resorption and destruction. It is suggested that PGE secreted by foam cells or giant cells could be responsible for the process of aseptic loosening.
View full abstract
-
K. ASADA, A. SHIMAZU, J. ABE, T. SASAKI, N. TANAKA, K. SAKAMOTO, H. SA ...
1984 Volume 13 Issue 3 Pages
1113-1119
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
We reported our aseptic loosening and revision total hip replacement cases which have been performed in our orthopedic department since 1967. Charnley type has 2.4% loosening hips but no revision cases, and Charnley-Müller type has 44% loosening hips and 13% revised hips. We tried to do statistical analysis of factors influencing the prosthetic loosening after total hip replacement by computer. About revision surgery, we discussed its indications and contra-indications, reported our techniques of revision surgery.
View full abstract
-
D. YUGUE, M. MATSUMOTO, N. YAMAMOTO, Y. NAKAMURA, Y. SAKAMOTO
1984 Volume 13 Issue 3 Pages
1120-1121
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
61 cases (70 hips) were operated by Judet's Cementless T. H. between november 1976 and august 1983 in our Orthopaedic Surgery Division. Patients aged from 28 to 69 years, 20 mens and 41 womens. They are 44 chronic O. A., 9aseptic necrosis, 2 traumatic coxarthrosis, 2 rheumatoid arthritis and etc.. As this total hip has charactaristic model and mechanisms, the operative technique is much more difficult than the others. On clinical result, 83% are excellent and good, 15% fair and 2% bad by criteria of Merle d'Augibné & Postel.
View full abstract
-
T. FUKUBAYASHI, T. TATEISHI
1984 Volume 13 Issue 3 Pages
1122-1125
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
Retrieval Analyses of the total hip prostheses were performed. 42 removed implants were examined using optical and scanning electron microscopy. In some cases surface roughness and load-torque curve were also measured. Numerous pitts, craters, and scratches were found in most of the cases. Wear rate of the UHMWPE was 0.12mm per year as an average. Surface roughness test showed more than 100μ roughness at the severely degradated cases. In these cases load-torque curve showed 2-5 times higher value than in normal cases. These degradation rates of the UHMWPE are well over our speculation. So further improvement of the implant materials are desired.
View full abstract
-
[in Japanese]
1984 Volume 13 Issue 3 Pages
1126
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
-
H. ONO, T. OKAZAKI
1984 Volume 13 Issue 3 Pages
1127-1130
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
On listening to speech sensorineural hearing impaired subjects are liable to miss the consonant part of a monosyllable and recognize only the following vowel. From psychoacoustic experiments we have found that emphasizing the consonant part could aid such subjects in their speech discriminating ability. We have therefore develope a hearing aid with a speech recognition system in which consonant and vowel sounds are separated.
After placing appropriare emphasis, the monosyllable is resynthesized and fed on-line to the earphone. With assurance of improved hearing for these patients, we developed a computer hearing aid with the speech recognition system.
View full abstract
-
H. AOKI, Y. SHIN, M. AKAO, R. KIKUCHI
1984 Volume 13 Issue 3 Pages
1131-1134
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
Sintered hydroxyapatite is known as a new implant material having excellent compatibility with bone and tooth tissues, and has began to be used for artificial bone and tooth root. In this study, sintered hydroxyapatite was designed for percutaneous device, The device and silicone rubber used as a control were percutaneously fixed through the skin of mongrel dogs. The soft tissue reaction around the implants at 2, 4 and 12 weeks was examined.Fibrous connective tissue with thickness of 50-800μm was formed around the hydroxyapatite, and inflammation and infection were not observed. Connective tissue with thickness of 400-1200um were observed around the silicone rubber. It was considered that the sintered hydroxyapatite had excellent compatibility with soft tissue as well as bone and tooth.
View full abstract
-
K. MABUCHI, M. MORITA, A. NISHIMURA, Y. TSUKAMOTO, M. YAMAMOTO, T. SAS ...
1984 Volume 13 Issue 3 Pages
1135-1138
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
In this paper authors introduce a new type of a surgical prosthesis: cylindric total knee prosthesis. Its femoral component is made by alumina ceramics. Its tibial component is made by ultra high molecular weight polyethylene. Their frictional surfaces are segments of a cylinder which radius is 25mm. Authors compared the performance of this prosthesis with other representative ones. The results of some experiments showed that this prosthesis has good performance.
View full abstract
-
N. SUGIYAMA, M. SHIMADA, M. URUNO, C. KADOYA, R. KOJIMA, I. SHINOHARA, ...
1984 Volume 13 Issue 3 Pages
1139-1142
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
Parameters of polymer-platelet interaction in reversible adhesion (K) and irreversible adhesion (K') were determined from the microsphere-column method. On the basis of K and K', platelet adhesivity on the block copolymer surfaces having hydrophilic-hydrophobic microphase separated structure was estimated. The platelet adhesivity in the initial stage of adhesion was found to depend on the hydrophilicity of polymer surfaces. The block copolymers were observed to exhibit an antithrombogenic property through the suppression on the platelet activation and aggregation i n the later stage of platelet adehsi on.
View full abstract
-
Y. MORI, S. NAGAOKA, R. TERADA, S. NISHIUMI, H. TANZAWA, A. KUWANO, H. ...
1984 Volume 13 Issue 3 Pages
1143-1146
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
The interactions of the hydrogel with long PEO chains with platelets have been investigated using arterio-venous shunt method between the carotid artery and jugular vein of rabbits. The introduction of the long PEO chains to the materials significantly prevented the thrombocytopenia and the reduction of clot retraction ability induced by the A-V shunt.
View full abstract
-
Y. NOZAKI, Y. YAMAMOTO, T. AKAIKE
1984 Volume 13 Issue 3 Pages
1147-1150
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
Contact activation (activation of blood coagulation factor XII) and adhesion of platelets on the oriented lipid surface with various electric charge were examined. Neutral lipid surface was found to inhibit the activation of factor XII, and also to inhibit the adhesion of platelets. On the other hand, anionic lipid layer activated the contact phase of coagulation and attracted more platelets than neutral surface. On cationic surface contact phase was not activated but platelets adhesion was rather strong. The results indicate that blood compatibility of neutral lipid surface is fairly high.
View full abstract
-
A. NAKAO, M. SHINOHARA, S. HOSHINO, K. ICHIKAWA, T. NONAMI, M. SUENAGA ...
1984 Volume 13 Issue 3 Pages
1151-1154
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
Blood coagulation activities have been measured on the surfaces of the synthetic materials including glass, plasticized polyvinylchloride (PVC), silicone rubber, hydrogel with long polyethyleneoxide chains (PEO), cationic hydrophilic polymer (PSD) and heparinized hydrophilic polymer (H-PSD). H-PSD effectively prevented the activation of the intrinsic coagulation factors by the complex formed between antithrombin III and heparin released from its surface. In the other materials, some differences in the activation of the intrinsic coagulation factors were found and discussed.
View full abstract
-
K. KIYOTO, Y. IDEZUKI, S. HAMABE, M. HAMAGUCHI, H. KOMORIYAMA, G. IKAR ...
1984 Volume 13 Issue 3 Pages
1155-1157
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
Antithrombogenic catheter coated with heparinized hydrophilic polymerer (H-RSD) has been developed. During 82' to 83' this catheter has been used in 45 patients as the indwelling catheter in the central vein, and the antithrombogenicity of the catheter has been evaluated. The catheter was placed in the central vein for the period from 4 days to 105 days (mean 35 days). Thrombus formation due to the catheter was examined by clinical observation, and by scanning electromicroscopy of the surface of these catheter after removal from the patients. Thrombus formation on the surface of the H-RSD catheters was compared with that of the polyvinyl carolide catheters. Marked thrombus formation was observed on the inner surface of polyvinyl chrolide catheter, however the thrombus formation was minimum in case of H-BPS catheters. The blood compatibi lily of the H-RSD catheter is excellent. The H-RSD catheter is suitable for use as the indwelling catheters where long-standing antithrombogenicity is mandatory.
View full abstract
-
[in Japanese]
1984 Volume 13 Issue 3 Pages
1158
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
-
S. MIYAZAKI, S. TAKEUCHI, M. SAKAMOTO, M. TAKADA
1984 Volume 13 Issue 3 Pages
1159-1162
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
Ethylene-vinyl acetate (EVAc) and ethylene-vinyl alcohol (EVA1) copolymers were evaluated as carriers for controlled release of drugs. Matrices composed of EVAc and EVA1 copolymers could be useful vihicles for implanted, inserted, or surface-applied delivery systems for hydrophobic and hydrophilic drugs, respectively.
View full abstract
-
T. TANI, M. KODAMA, T. OKA, K. HANASAWA, T. HASHIMOTO, Y. NAKANE, S. N ...
1984 Volume 13 Issue 3 Pages
1163-1167
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
Lipopolysaccharide (LPS) from E. Coli could be immobilized to the insoluble fiber(LPS-F). This novel fiber (LPS-F) had an anticomplementary effect and decreased lethal activity in mouse by injection of activated human serum, but had not pyrogenicity. Anti-tumor effectiveness of LPS-F were examined by the direct hemoperfusion on the Vx2 tumor bearing rabbits with the column contained it. And it was recognized that LPS-F had the anti-tumor activities.
View full abstract
-
M. YOSHIDA, M. ASANO, I. KAETSU, H. YAMANAKA, K. NAKAI, H. YUASA, K. S ...
1984 Volume 13 Issue 3 Pages
1168-1171
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
The radiation polymerized vinyl copolymer LH-RH analogue delivery composites having sandwich structure were implanted subcutaneously in the back of male Wistar rats. The significant physiological response in rat prostate was observed after TAP144-containing composite implantation. Furthermore, the composite was applied to prostatic cancer and implanted subcutaneously for 82 days. This patient responded to treatment in terms of clinical regression of tumor.
View full abstract
-
-Basic studies and the clinical application-
A. SUGITACHI, Y. TAKATSUKA, I. SAKAMOTO, K. TAKAGI
1984 Volume 13 Issue 3 Pages
1172-1175
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
Adriamycin (ADM) and Mitomycin were individually mobilized on absorbable gelatin materials, together with a blood clotting factor, Factor XIII and Thrombin, to provide a new thrombotic agent for Transcatheter Arterial Chemo-Embolization (TACE). The basic studies confirmed that the materials remarkably enhanced local accumulation of fibrin and release of the immnobilized ADM was slow. The materials were clinically applied in preoperative TACE for 17 patients with locally advanced breast cnacer. Therapeutic effects of the TACE were both clinically and surgicopathologically excellent.
View full abstract
-
-with polylactic acid-
M. HIRANO, M. SAKATOKU, R. YAMASHITA, T. IWA
1984 Volume 13 Issue 3 Pages
1176-1179
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
As slow released anticancer drug 5-Fu polylactic acid composite (F-PLA needle) was newly prepared. In the present studies, the properties of this preparation were clarified, and its anticancer effect was investigated. The findings are as follows. 1) The release speed of 5-Fu from the F-PLA needle was found to be slower than from the S-Fu-polyglycolic acid composite (F-PGA needle). 2) When two F-PLA needles were implanted in each tumors of rats which received subcutaneous transplants of AH 130, tumor proliferation was markedly inhibited with an inhibition rate of 94.4% at 12 days after implantation. Based on these results, it was found that the F-PLA needle was longer-acting than F-PGA needle and had marked anticancer effect.
View full abstract
-
M. SAKATOKU, M. HIRANO, M. ASANO, T. IWA, T. KONDO, M. ARAKAWA
1984 Volume 13 Issue 3 Pages
1180-1183
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
We prepared 5FU- polylactic acid-microcapsule (5FU-PLA-mc). 5FU was microencapsulated with polylactic acid based on the organic phase separation technique. The size of 5FU-PLA-mc was about 200μm in diameter. The rate of 5FU content in capsule was about 40%. The release rate of 5FU from 5FU-PLA-mc was 100% at 50hrs rotating incubation, When 5FU-PLA-mc suspention was injected into the femoral artery of the rabbit implanted VX2 tumor at thigh, it was found that tumor vessels were embolized from smoll artery to large artery on the angiogram. Tumor redction was found on the rabbit injected 5FU-PLA-mc 75mg suspention into the femoral artery, but enormous tumor growing was found on the rabbit of which femoral artery was only ligated and dissected. Polyiactic acrd was inetabolizabie and absorbale, so it was suitable for the drug- carrier material. From the result of experiment, it was suggested that 5FU-PLA-mc was useful in the cancer chemotherapy.
View full abstract
-
[in Japanese]
1984 Volume 13 Issue 3 Pages
1184
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
-
A. MATSUKAWA, T. SEGAWA, K. SATA, H. INAMOTO
1984 Volume 13 Issue 3 Pages
1185-1188
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
The effect of extracts of plastics in medical use on DNA synthesis by human lymphocytes in culture was investigated. The addition of distilled water, saline and 5% ethanolsaline extracts of plasticizer free polyvinylchloride (PVC) and etylene-vinylacetate copolymer (EVA) into the culture had no effect on DNA synthesis. However, ethanol extracts of PVC and EVA inhibited DNA synthesis. Extracts of polyethylene (PE) and PE-EVA-PE laminated film with four kinds of eluant showed no inhibition. Human lymphocytes and mouse L cells showed a similar response to the extracts of plastics.
View full abstract
-
Y. IMAI, A. WATANABE
1984 Volume 13 Issue 3 Pages
1189-1192
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
The segmented polyester (SPE) based on a polyoxytetramethylene soft segment and a poly (tetramethylene terephthalate) hard segment was implanted subcutaneously in rats for up to 28 months. Tissue response and material change was compared with poly (ethylene terephthalate) (PET). No significant difference between SPE and PET was observed in tissue response and tumorigenicity, and tensile property change of SPE was minimal.
View full abstract
-
Y. IMAI, A. WATANABE
1984 Volume 13 Issue 3 Pages
1193-1196
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
Fluorine-containing homopolymers and copolymers consisting of fluoroethylenes, fluoropropylene, perfluoroalkyl vinyl ether, ethylene and propylene were evaluated for their biocompatibility by cell culture method. Initial cell attachment increased with decrease in the number of fluorine atom in the monomer units. Only perfluoropolymers showed a biocompatibility considerably different from the other polymers.
View full abstract
-
-histological evaluation-
T. TAMURA, T. NAKAMURA, K. OKADA, H. MIZUNO, Y. SHIMIZU, M. ITO, T. TE ...
1984 Volume 13 Issue 3 Pages
1197-1200
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
We have prepared new hydrogel from Polyvinyl alcohol wich has rubber-like-elasticity. Its water content is 80-90wt% but it is insoluble in water. Its medical application has been studied. During the implantation, its water content did not change and it did not adhere to the tissue around it. Histologically inflammation, degeneration and granulation were not noticed at the tissue around the implanted PVA gel. This new material was examined for non-adhesive membrane in the living body.
View full abstract
-
A. MARUYAMA, E. SENDA, N. YOSHINO, T. TSURUTA, K. KAAOKA, T. OKANO, Y. ...
1984 Volume 13 Issue 3 Pages
1201-1204
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
PolyHEMA/Polyamine comb-type copolymer (HA) having microdomain structure was evaluated as a substrate for cell adhesion chromatography used for separation of lymphocyte subpopulation. HA-column was found to separate B-cell from T-cell more effectively than Nyloncolumn, which has been used for separation of lymphocyte subpopulation. Moreover, efficacy of the HA-column was retained at high value even though there exists no serum component, such as albumin.
View full abstract
-
N. NEGISHI, Y. TOMITA, M. KIKUCHI
1984 Volume 13 Issue 3 Pages
1205-1208
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
The purpose in this study is to give the following method; Releasing of drugs such as anticancer from polymer matrices is controlled by ultrasonic irradiation from the outside of living body and it is applied to thermo-chemotherapy in cancer and so on. In this session, we proposed a new method to regulate the release of anticancer in time and space by using ultrasonic irradiation and by adding of hydroxyapatite to collagen matrix.
View full abstract
-
M. ANDO, N. NAKAJIMA, S. ADACHI, [in Japanese], E. TOMITA, [in Japanes ...
1984 Volume 13 Issue 3 Pages
1209-1212
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
The standard surgical procedure for the distal arch and descending thoracic aneurysm is resection of aneurysm and orthotopic graft replacement. However in certain situation, this procedure is difficult to apply. Then extra-anatomical bypass from ascending to abdominal aorta with exclusion of aneurysm is better than conventional procedure. For the simplification of procedure, we have designed our own permanent aortic clamp for the exclusion of aneurysmal cavity and have already clinically applied on 8 patients. Our own aortic clamp has been very easy to use. The technique and operative results will be discussed.
View full abstract
-
Y. OKA, T. MIYAMOTO, H. TERAI, H. SOO, K. SUYAMA, K. TAKAGI
1984 Volume 13 Issue 3 Pages
1213-1216
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
An experimental study was performed in mongrel dogs for examination of thrombogenicity of the urokinase-treated vascular shunt tube. Urokinase was immobilized on polyvinyl chloride tube. Bypass was carried out for 2 hours period between the ascending aorta and the abdominal aorta. There was no thrombus formation at the inner side of all the tube, however the thrombus was seen in some cases at the site of insertion into the aorta. The remained fibrinolytic activity of the tube decreased remarkably in the outer layer both end of these tube. In the high activity urokinase-treated tubes (x3, UK) there was no thrombus formation. These results suggest that high activity urokinase-treated shunt tube would be useful for clinical application.
View full abstract
-
T. HATTA, T. SHIDA, H. NAKAMURA, M. MIYASHITA, K. NAKAMURA
1984 Volume 13 Issue 3 Pages
1217-1220
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
Surgical closure of the ventricular septal rupture (VSR) following acute myocardial infarction (AMI) is still one of the most formidable procedure to cardiac surgeon. While the surgical results in chronic stage are satisfactory, the results in acute stage are still miserable because of friability of the infarcted myocardial muscle. This experimental work was undertaken to develop a new method to close the VSR Temporarily. A couple of an umbrella made of stainless-steel ribs covered with Dacron fabrics are used to close the VSR with an aid of specially designed introducer. Closure of the experimental VSR with this umbrella was successful in eight dogs among seventeen dogs. One dog was sacrificed three weeks after closure of the VSR. The macroscopic and microscopic findings showed complete closure of the VSR with good organization of the Dacron fabric. In conclusion, this umbrella method for closure of the VSR, seems to be attractive and promising but further modification is necessary before its clinical use.
View full abstract
-
[in Japanese]
1984 Volume 13 Issue 3 Pages
1221
Published: June 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL
FREE ACCESS
