Abstract
In the case of the dialysis patient, the depression of the arterial pressure mainly comes from the blood volume reduction. Though usual trend of blood pressure in hemodialysis is monotonic reduction, the continuous or occasional hypertension is also observable. The hypertension is thought to be the result of regulation efforts against the blood volume decrease which was detected as right atrial pressure (Pra), where the regulation performance was improved with enhanced cardio-contraction characteristics through HD. Based on this ideas, a circulation system model was rebuilt in this report introducing the Pra receptor as a volume receptor, which, along with the arterio-receptor, controls the circulation system consisting from 3-compartment model, cardiac model and blood vessel model. This model was found to simulate well the clinical data for both hypo-and hypertension.