Abstract
Post-pump syndrome occurs sometimes after cardiopulmonary bypass. It is thought that C3a and C5a play a causative role in the induction of the syndrome. The following conclusions about cardiopulmonary bypass using O2 bubble oxygenator and membrane oxygenator were obtained. (1) Maximum decrease of WBC count occuredrto 61.7% at 30 min. followed by rebound. (2) Platelet count, C3, C4 and CH50 did not change. (3) C3a levels incresed to about 15 folds of pre-bypass level. No difference of C3a levels was observed between venous line and arterial line. (4) C5a levels raised either at venous line and arterial line.