Abstract
Aluminum transport and dialysance during hemodialysis were examined in thirty chronic hemodialysis patients. Serum aluminum levels in thirty volunteer outpatients tended to decrease after 5-hour dialysis (6.35±3.02μg/dl before hemodialysis; 5.41±2.60μg/dl after hemodialysis). Serum aluminum levels were 0.6±0.2μg/dl in normal subjects. The decrease was mainly due to diffusion despite hemoconcentration evidenced by a significant increase in the hematocrit and total serum protein during dialysis. To study the changes resulting from diffusion, we measured aluminum in the arterial blood and in the dialysate at the inflow and outflow sites of the dialyzer. Aluminum diffused across the dialyzer from the blood to the dialysate in twentythree cases and into the blood in seven others. Aluminum dialysance of 30 patients was 13.34±22.1ml/min. The relationship between aluminum dialysance and ultrafiltrable aluminum levels was a significant correlation (r=0.80, p<0.005).
