1987 Volume 16 Issue 2 Pages 834-837
We studied a removal capacity of Al, Fe and clinical efficiency by PPHD using protein leaking membrane dialyzer and DFO therapy (10-30mg/kg, weekly) for AABD 10 cases and hemosiderosis 5 cases. The removal capacity of Al-DFO complex by PPHD was significantly higher than by usual HD. Al and Fe were together removed by DFO and PPHD. All AABD cases reduced bone pain by administrated DFO to one from three times, and one case with multiple pathological fructures had healed after 3 months. Hemosiderosis cases did not clearly take effect, but serum ferritin decreased significantly after 3 months, so DFO therapy may be stopped the development of hemosiderosis. The method of weekly administrated DFO was rare to find side effects and took sufficient effects clinically. In conclusion, PPHD can carry out easily and is useful the removal of Al-DFO or Fe-DFO complex.
