Abstract
Four types of modules with high performance membrane were examined during in vitro study. β2-microglobulin (BMG) concentrations of a feed tank were constant in cellulosic membranes, regenerated cellulose (RC) and cellulose triacetate (CTA), whereas synthetic polymer membranes, polysulfone (PS) and polymethylmethacrylate (PMMA), showed membrane adsorption and/or plugging in constant-rate filtration experiments with a closed circuit. Time-averaged sieving coefficients for BMG were 0.444, 0.924 and 0.516 for RC, CTA and PS, respectively. Overall mass transfer coefficients for BMG were obtained as 3.70μm/min for RC and 17.83 for CTA by dialysis experiments.