Abstract
PVC or silicone with synthetic surface of very high water content were implanted abdominally in mice for up to 6 months. Hydrophilic surface modification was attaind by the undercoating formed a reactive functional group and the covalently bonded hydrophilic coating which is a copolymer of methyl vinyl ether and maleic anhydride. As a result, the hydrophilic coating layer obstructed adhesion, foreign body reaction, thick capsule formation, and chronic peritonitis. This finding suggests that this hydrophilic synthetic surface contributed considerable biocompatibility.
