ANTITHROMBOGENICITY AND HEALING CHARACTERISTICS OF A SMALL-CALIBER BIOLOGICAL VASCULAR GRAFT

Abstract

We have developed a small-caliber vascular graft with an ID of 3mm by chemical modification of sheep carotid artery using a hydrophilic crosslinker, polyepoxy compounds (PC) and implanted in the carotid artery of a dog. The inner surface of every patent graft was clean without thrombi. Microscopic observation showed the anastomotic site of the graft on 7th day was covered with endothelial cells. We concluded our developed graft had a nice healing characteristics and good antithrombogenicity.