Abstract
The three polyacrylonitrile membrane dialyzers, PNF-17CX2(CX), PAN-17DX(DX) and Filtral 16(F) were tested for biocompatibility and clinical performance. Eight patients on maintenance hemodialysis took part in this study. They changes of leucocyte counts, platelet counts and C3a at 15 min during the hemodialysis were the same degrees in the three dialyzers. The changes of plateletfactor-4 and activated coagulation time at 15 min during the hemodialysis and residual blood volume within the module fibers after each dialysis session were greater in CX than in other two dialyzers. In conclusion, DX shows the antithrombogenicity better than CX, and as same as F.
