Abstract
Influences of dialysis(HD) time under fixed urea index(UI) on phosphate removal was evaluated among 3.5, 4.0 and 4.Shr HD in which blood flow rate (QB) was changed from 210±20ml/min in 3.5hr HD, to 180±20ml/min in 4.Ohr HD and to 155±25ml/min in 4.5hr HD. Among three HD groups, no significant differences were observed in pre-HD BUN, UA, Cr and P concentrations, redution rates and elimination into dialysate of these substances, though clearances of them increased according to QB. Time course of P removal into dialysate showed gradual decreases along with HD time in 3.5 and 4.Ohr HD. During 4.5hr HD, it reached to plateau after 3.Ohr of HD, which might be due to inflow of P from extra-vascular space. P removal in short time HD strongly depended on pre-HD serum P level. It is concluded that P elimination was not affected by dialysis time at least between 3.5 to 4.5hr under fixed UI.
