Clinical study of extracapillary blood flow type Univox-IC hollow fiber membrane oxygenator

Abstract

We clinically evaluated the Univox-IC membrane oxygenator comparing with Cobe Membrane Lung (CML). The Univox-IC membrane oxygenator was used for open heart surgery in 60 patients and the CML was used for 25 patients. The priming volume of the Univox-IC was 220ml, smaller than the CML. In addition to small priming volume, the Univox-IC has excellent O₂ transfer rate and CO₂ transfer rate and good heat exchange efficacy. The Univox-IC has low pressure drop than previously reported extracapillary blood flow type hollow fiber membrane oxygenator. Increasing rate of free plasma hemoglobin in the Univox-IC was lower than the CML. Preservation rate of the platelet was good in two groups