Effects of intraaortic balloon pumping on the acute mitral insufficiency and ventricular septal perforation

Abstract

The effects of intraaortic balloon pumping (IABP) on the acute mitral insufficiency and ventricular septal perforation were studied in 21 mongrel dogs.
Mitral regurgitation was made by left ventrcculo-atrial extracardiac bypass with electro-magnetic flow meter. Ventricular septal perforation was simultaneously made by extracardiac bypass between left ventricle and right ventricle. By that method, the influence of IABP on regurgitant and shunt flow was clearly documented.
IABP reduced left ventricular pressure by 9 to 12.8% and augmented cardiac output by 3 to 16%. Mean aortic root diastolic pressure was elevated in average 11mmHg. Regurgitant flow was reduced by 12.6-14.6%. L-R shunt flow was reduced by 18%. There were not significant deference between normal and ischemic dogs.
Effects of IABP reducing regurgitant and shunt flow are dependent on decrement of the impedance to left ventricular ejection.
It was concluded in this experiment that IABP reduced left ventricular systolic pressure, thereby reduced regurgitant and shunt flow.