人工臓器
Online ISSN : 1883-6097
Print ISSN : 0300-0818
ISSN-L : 0300-0818
悪性腫瘍の治療時(L-asparaginase使用)に生ずるアンモニア除去装置に関する研究
山田 明夫町山 悦子壁井 信之菊地 真桜井 靖久木原 一彦伊東 光一
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1978 年 7 巻 1 号 p. 112-115

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High ammonia concentration of blood was seen ingiving L-asparaginase and L-arginine. So that the necessary equipment to eliminate ammonia was needed. On account of high rapid elimination of ammonia electro-dialyser was used. The menbranes of CMV and AMV as electrodialyser were used and electrified between them. Electro-dialyser to use ultrafiltration has high point of rimiting current density. So that the effects on electro-dialyser were quantitatively analysed in vivo experiments. With increasing electrical current, the rapidity and efficiency of blood ammonia removal was increased. With maintaing acid base equilibrium, electrolyte (Na, K and ci) and osmotic pressure, ammonia was eliminated rapidly.

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