人工臓器
Online ISSN : 1883-6097
Print ISSN : 0300-0818
ISSN-L : 0300-0818
細菌による尿素・アンモニアの有用物質への交換能の医療への応用
阿岸 鉄三太田 和夫吉田 浩一
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1978 年 7 巻 1 号 p. 109-111

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Non-protein N substances such as urea and ammonia are converted to amino acid and protein in the rumen of ruminant by virtue of microorganisms. Considering the possible application in hepatic and uremic patients, converting activity of micrococcus glutamicus of urea and ammonia to L-glutamate was examined. Fresh, lyophilized or sonicated micrococcus glutamicus reduced urea concentration and produced L-glutamate in the medium. Oral or ex vivo application of the treated. microorganism is suggested to be useful after sophistication of methodology in hepatic and uremic patients.

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© 一般社団法人 日本人工臓器学会
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