血液透析回路用各種ポリ塩化ビニルの医用材料としての評価

抄録

Eight medical grade poly (vinyl chloride) (PVC) used mainly in hemodialysis were evaluated and compared with medical grade silicone rubber by our in vitro test program, which consists of repeated extraction test, hemolysis test and tissue culture test. PVC materials were more hemolytic, more hemoglobin denaturative and more inhibitive of cell growth than silicone rubber. The results were considerably different from one another among the PVC materials tested. Two PVC seemed comparatively safer than the others. It is recommended to select and to use safer materials among the PVC products available.