Takagi's pump (Double-chambered alternate pumping paracorporeal device) has been tested in 50 dogs for last one year.
Results obtained in left heart bypass with this device were as follows.
1) Bypass flow rate was always maintained at the higher level than usual cardiac output, such as 170ml/kg/min up to 3 months. 2) In sever left heart failure induced by the ligation of almost all major branches from anterior descending, circumflex, and posterior descending coronary artery to the left ventricular wall, dogs survived up to 5 day with almost normal appearance.
These results suggest that our device may guarantee the survival even in the sever left heart failure of almost no cardiac output.