Cleansing effect of ultrasound on the dialysis membrane was investigated by two experiments.
In the first experiment, blood flow from a dog was devided equally into two parts and continuously ultrasonicirradiated hemodialysis in one part, non-irradiated hemodialysis as a control in another part were performed for 6 hours.
In the second experiment, using the same equipment but flowing saline in equal flow rate in place of the blood ultrasonic irradiation in one part and non-irradiation as a control in another part on both used hemodialysis membranes actually in uremic patients were performed simultaneously for several different periods.
Adhered protein quantities on the irradiated or non-irradiated membranes were measured after each experiments and cleansing rates were calculated. High cleansing rates by ultrasonic irradiation were shown in almost of both experiments but wrose cleansing rate was observed in 100KHZ, 50W ultrasonic irradiation in the first experiment.
Hemolysis progressed in proportion to irradiation time was observed in 19. 19.5, 29, and 50KHZ, but not in 100KHZ.
