Biocompatibilities of the PMMA-HFAK were compared with those of the cellulosic HFAK through the analyses of the deposits on them used clinically or experimentally. The amounts of the proteins deposited on them were the same for both HFAK. Morphological changes of adhered platelets were milder for PMMA-HFAK than for cellulosic HFAK. More deposits were found on the arterial side than on the venous side. The profound transient leukopenia was found in the dog in vivo studies for cellulosic HFAK, but the phenomenon was moderate for PMMA-HFAK.
