人工臓器
Online ISSN : 1883-6097
Print ISSN : 0300-0818
ISSN-L : 0300-0818
試作コラーゲン交織管の小血管移植への応用
佐々木 久雄中矢 洋宇津 尾明
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1980 年 9 巻 2 号 p. 613-616

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A compound prosthetic graft, which was woven with alternate yarns of nonabsorbable (Tetron) and absorbable (Collagen) fibers, was made and we called it as CoT graft. Though the patency of CoT graft of 8mm in diameter was 100%, the one of 4mm was 0%.
The study was done in order to know the causes of the occlusion of small caliber CoT graft.
Five kinds of CoT draft, which were different respectively in points, tanning, heating and the size of caliber, were implanted in arteries of 9 dogs in periods of 1 to 21 days. Scanning electron microscopic study was done.
The results. (1) How to treat collagen for tanning; CoT treated by 0.95% gluteraldehyde solution got pseudointima for motion ealier than one treated by 0.35% gluteraldehyde solution.
(2) Patency of CoT graft heated was better than the one non-heated.
(3) The size of the caliber of CoT graft was not related very much with a cause of occlusion of CoT graft is early stage.
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