抄録
The edible species of Nostoc are unique cyanobacteria because they can grow in some extreme environments, and some of these species are rare. Anti-hyaluronidase activity and sugar composition of the extracts were compared among five edible Nostoc strains which were cultured using 180 liter large scale reactor. The IC50 against hyaluronidase of the extracts of Nostoc sphaericum, Nostoc flagelliforme and Nostoc verrucosum were 14.4, 46.5 and 56.2 μg mL -1, respectively. These anti-hyaluronidase activities were higher than disodium cromoglycate which is known as an anti-allergic drug and used as a positive control substance. The ratio of glucuronic acid in constituent sugar of N. sphaericum extract was 13.3%, it was the highest among the five strains tested. The extract of N. sphaericum had the highest yield and highest anti-hyaluronidase activity when compared with the other four Nostoc strains.
