Mid-infrared photothermal microscopy

抄録

Mid-infrared photothermal (MIP) microscopy is an emerging imaging technique that visualizes mid-infrared absorption arising from molecular vibrations with high spatial resolution through visible-light detection. In this review, we focus on mid-infrared photothermal quantitative phase imaging (MIP-QPI), a technology recently developed by our group. We present recent advancements, including high-sensitivity, video-rate chemical imaging, and enhanced spatial resolution. In addition, we discuss novel applications such as the direct visualization of intracellular heat diffusion and thermophoresis, underscoring the promising potential of MIP-QPI for life science research.