The Influence of 5-n-Buthyl-1-Cyclohexyl-2, 4, 6-Trioxoperhydropyrimidine (BCP) on Antibody Formation

Abstract

The influence of 5-n-buthyl-1-cyclohexyl-2, 4, 6-trioxoperhydropyrimidine (BCP) on hemolysin formation against sheep red cells in mice was observed in comparison with that of cortisone. The drug was administered subcutaneously once daily for 4 days, starting from the 3rd day before (I), at the same time with (II) and on the 3rd day after (III) the intraperitoneal sensitization. While BCP gave no influence upon the antibody formation in (I), (II) and (III), cortisone suppressed markedly the hemolysin titer in (I) and (II), but showed no influence in (III).