Evaluation of effectiveness of high-flow/high-volume continuous hemodiafiltration in 34 patients with septic shock and acute kidney injury

Abstract

Recently, sepsis is commonly treated by acute blood purification. In this retrospective study, we examined 34 patients with septic shock and acute kidney injury who were treated with high-flow/high-volume continuous hemodiafiltration (CHDF) in order to evaluate the parameters relating to circulation and renal function. Mean arterial pressure and urine output increased two and six hours, respectively, after initiation of treatment. Vascular resistance also increased and body temperature decreased after treatment. Our findings suggest that high-flow/high-volume CHDF may improve circulatory and renal dysfunction in sepsis patients.