抄録
Adenosine 3', 5'-monophosphate-dependent protein kinases in most tissues and organs from various mammalian species appear to be similar enzymes which show rather broad and identical spectra of phosphate acceptor proteins, and to phosphor- ylate simultaneonsly several regulatory enzymes and functional proteins, such as glycogen phosphorylase b kinase, glycogen synthetase, lipase, histone, membrane proteins, and ribosomal proteins. The evidence suggests that the action of hormone seems to be amplified by succesive activations of two consecutive enzymes, adenyl cyclase and protein kinase, resulting in the pleiotropic control of various biochem- ical reactions in each target cell.
