臨床化学
Online ISSN : 2187-4077
Print ISSN : 0370-5633
ISSN-L : 0370-5633
ブドウ糖投与後運動負荷の糖・脂質代謝に及ぼす影響
本間 聖康井関 敏之赤井 俊洋奥田 清
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1982 年 11 巻 2 号 p. 104-114

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To decide an appropriate application of kinesitherapy to treat diabetics, effects of exercise on glucose and lipids metabolism were examined using 4 healthy subjects.
On the same subject, 13 test conditions were set in consideration of intensity and duration of exercise as well as relative starting time of the exercise after oral glucose administration, and the changes of BS, IRI, FFA and TG in the course of time were me asured. That is, using a treadmill, 3 kinds of exercises were given, namely, 60 minutes for 40%, 30 minutes fo r60% and 15 minutes for 80% of VO2 max., respectively, and exercise starting time was set to be immediately, 30 minutes and 60 minutes after glucose admin istration.
When the exercises of 40% and 60% VO2 max. were started immediately after glucose administration, the rises of BS and IRI were inhibited. Especially IRI concentration at the end of exercise showed a significant reduction (p<0.05) compared to that of oral glucose administration during the rest. When such an exercise was started 30 minutes and 60 minutes later, the reduction of BS and IRI was accelerated, and at the end of exercise nearly the same level as those of fasting levels. Such tendency was more remarkable in the exercise of 60% VO2 max. than that of 40% VO2 max. On the other hand, in the exercise of 80% VO2 max., it showed the higher BS and IRI concentrations compared to those of oral glucose administration during the rest time.
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