抄録
In a patient with lgA (K) myelomatosis, total calcium level in the serum was found to be relatively high although ionized calcium was normal and albumin was low (total calcium, 2.5 mmol/l; ionized calcium, 1.15 mmol/l; albumin, 26g/l).
By a study of calcium-binding capacity of serum protein fractions obtained with the gel chromatographic method of Toffaletti et al.(1977), extent of calcium-binding capacity of the lgA (K) monoclonal component purified from the patient's serum was 1.22×10-2 mmol calcium per 1 g Protein whereas those of albumin and globlin from normal subjects were 1, 05×10-2 and 0.44×10-2mmol/g respectively.
Accordingly, the lgA (K) monoclonal component of the patient is the globulin which has almost the same affinity for calcium as albumin.
