抄録
A systematic study on the changes in levels of γ-glutamyltranspeptidase (GGT), protein and creatinine in amniotic fluid has been made. GGT activity in amiotic fluid showed a gradual decline with advancing pregnancy. Highest enzymatic activity was observed during 12-16 weeks of gestation. The correlation between GGT activity and protein content was found to be significant statistically. On the other hand a significant negative correlation between GGT activity and creatinine concentration was also observed in amniotic fluid. The GGT activity in amniotic fluid at term was comparable to the enzyme level in the maternal serum. The GGT activity in the umbilical-cord serum was found to be 10 fold higher than that of serum and amniotic fluid at term. No variation in the levels of serum GGT during different stages of pregnancy was noticed.
