抄録
Urinary 17-Ketosteroid Sulfates (17-KS-S), 17-KS Glucuronides (17-KS-G) and 17-Hydroxycorticosteroid Glucuronides (17-OHCS-G) were determined in patients with Cushing's Syndrome, with Addison's Disease (administered with high amounts of cortisol), with nonendocrine diseases etc. and normal adults.
In the above subjects 17-KS-G correlated well with 17-OHCS-G, but 17-KS-S did not correlate: Dissociation of 17-KS-S and the former two excretion was observed.
Measurement of urinary 17-KS-S, consisting of storage form adrenal androgens, Dehydroepiandrosterone-S (DHA-S), Androsterone-S (A-S), etc., is useful not only for diagnosis of adrenocortical diseases, but for determining severity of non-endocrine diseases.
